Antioxidants have an important role in preventing chronic inflammatory diseases of the gastrointestinal tract. They have an impact on preventing inflammatory process in the stomach and duodenum. The inflammation is prevented through the impact on the free radicals. Free radicals are responsible for the formation of ulcers and the antioxidants can block free radicals before they could do damage. Similar natural and diverse antioxidants prevent intestinal inflammatory processes and therefore prevent chronic inflammatory diseases of the gastrointestinal tract. More severe forms of those diseases are ulcerative colitis and Chron’s disease that have numerous consequences for the entire organism. When the disease is already developed, antioxidants have a beneficial effect on its course. By reducing the inflammation, they stop the pathological processes, can lead to improvement of the chronic situation in the intestine, and therefore could aid in the process of recovery.